{"id":1061,"date":"2013-06-29T20:37:04","date_gmt":"2013-06-30T00:37:04","guid":{"rendered":"http:\/\/blogviejo.sld.cu\/oserranob\/?p=1061"},"modified":"2013-06-29T20:37:04","modified_gmt":"2013-06-30T00:37:04","slug":"mutaciones-conducen-a-pubertad-precoz","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2013\/06\/29\/mutaciones-conducen-a-pubertad-precoz\/","title":{"rendered":"Mutaciones conducen a pubertad precoz"},"content":{"rendered":"<p>Las mutaciones que afectan al gen <a title=\"Informaci\u00f3n sobre el gen\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/7681\" target=\"_blank\">MKRN3<\/a> pueden ser causa de un temprano inicio de la pubertad e, indirectamente, de los <a href=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2013\/06\/NEJM.gif\"><img loading=\"lazy\" class=\"alignright size-full wp-image-1062\" style=\"border: 1px solid black;margin: 5px\" src=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2013\/06\/NEJM.gif\" alt=\"\" width=\"120\" height=\"28\" \/><\/a>trastornos y riesgos para la salud que ello provoca. El hallazgo y sus implicaciones aparecen en <em>Abreu AP, Dauber A, Macedo DB, Noel SD, Brito VN, Gill JC et al. <a title=\"Texto completo en ingl\u00e9s\" href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1302160#t=article\" target=\"_blank\">Central Precocious Puberty Caused by Mutations in the Imprinted Gene MKRN3<\/a>. N Engl J Med 2013; 368:2467-2475<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Las mutaciones que afectan al gen MKRN3 pueden ser causa de un temprano inicio de la pubertad e, indirectamente, de los trastornos y riesgos para la salud que ello provoca. El hallazgo y sus implicaciones aparecen en Abreu AP, Dauber A, Macedo DB, Noel SD, Brito VN, Gill JC et al. Central Precocious Puberty Caused [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[11,15,21],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1061"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=1061"}],"version-history":[{"count":0,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1061\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=1061"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=1061"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=1061"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}