{"id":1066,"date":"2013-06-29T21:17:57","date_gmt":"2013-06-30T01:17:57","guid":{"rendered":"http:\/\/blogviejo.sld.cu\/oserranob\/?p=1066"},"modified":"2013-06-29T21:17:57","modified_gmt":"2013-06-30T01:17:57","slug":"ubican-loci-para-cardiopatias-congenitas","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2013\/06\/29\/ubican-loci-para-cardiopatias-congenitas\/","title":{"rendered":"Ubican loci para cardiopat\u00edas cong\u00e9nitas"},"content":{"rendered":"<p>Una regi\u00f3n del cromosoma 4p16, cercana a los genes <a title=\"Informaci\u00f3n sobre el gen\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/4487\" target=\"_blank\">MSX1<\/a> y <a title=\"Informaci\u00f3n sobre el gen\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/53407\" target=\"_blank\">STX18<\/a>, se asocia con el defecto del septo auricular <em>ostium secundum<\/em> (<em>Cordell HJ, Bentham J, Topf A, Zelenika D, Heath S, Mamsoula C et al. <strong><a title=\"Texto completo en ingl\u00e9s\" href=\"http:\/\/www.nature.com\/ng\/journal\/vaop\/ncurrent\/full\/ng.2637.html\" target=\"_blank\">Genome-wide  association study of multiple congenital heart disease phenotypes  identifies a susceptibility locus for atrial septal defect at chromosome  4p16<\/a><\/strong>. Nature Genetics 2013<\/em>;<em>45:822\u2013824<\/em>), mientras en poblaciones chinas se encontr\u00f3 una relaci\u00f3n significativa para las regiones 1p12 y 4q31.1 (<em>Hu Z, Shi Y, Mo X, Zhao B, Lin Y, Yang S et al. <strong><a title=\"Texto completo en ingl\u00e9s\" href=\"http:\/\/www.nature.com\/ng\/journal\/vaop\/ncurrent\/full\/ng.2636.html\" target=\"_blank\">A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations<\/a><\/strong>. Nature Genetics 2013;45:818-821<\/em>).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Una regi\u00f3n del cromosoma 4p16, cercana a los genes MSX1 y STX18, se asocia con el defecto del septo auricular ostium secundum (Cordell HJ, Bentham J, Topf A, Zelenika D, Heath S, Mamsoula C et al. Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[15,21,29],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1066"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=1066"}],"version-history":[{"count":0,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1066\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=1066"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=1066"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=1066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}