{"id":1070,"date":"2013-06-29T21:27:26","date_gmt":"2013-06-30T01:27:26","guid":{"rendered":"http:\/\/blogviejo.sld.cu\/oserranob\/?p=1070"},"modified":"2013-06-29T21:27:26","modified_gmt":"2013-06-30T01:27:26","slug":"nuevos-elementos-etiologicos-en-esclerosis-lateral-amiotrofica","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2013\/06\/29\/nuevos-elementos-etiologicos-en-esclerosis-lateral-amiotrofica\/","title":{"rendered":"Nuevos elementos etiol\u00f3gicos en esclerosis lateral amiotr\u00f3fica"},"content":{"rendered":"<p>La secuenciaci\u00f3n del exoma de 47 pacientes con <a title=\"Informaci\u00f3n sobre la enfermedad\" href=\"http:\/\/omim.org\/entry\/105400?search=ALS&amp;highlight=als\" target=\"_blank\">esclerosis lateral amiotr\u00f3fica<\/a> revel\u00f3 la existencia de mutaciones en el gen de la <a href=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2013\/06\/130629-als.jpg\"><img loading=\"lazy\" class=\"alignright size-thumbnail wp-image-1071\" style=\"border: 1px solid black;margin: 5px\" src=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2013\/06\/130629-als-150x150.jpg\" alt=\"\" width=\"77\" height=\"77\" \/><\/a>mol\u00e9cula <a title=\"Informaci\u00f3n sobre el gen\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/26039\" target=\"_blank\">SS18L1<\/a>, tambi\u00e9n conocida como CREST. Las aplicaciones potenciales del hallazgo son comentadas en <em>Chesi A, Staahl BT, Jovicic A, Couthouis J, Fasolino M, Rapahel AR, Yamazaki T. <a title=\"Texto completo en ingl\u00e9s\" href=\"http:\/\/www.nature.com\/neuro\/journal\/v16\/n7\/full\/nn.3412.html\" target=\"_blank\"><strong>Exome sequencing to identify de novo mutations in sporadic ALS trios<\/strong><\/a>. Nature Neuroscience 2013;16:851\u2013855<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>La secuenciaci\u00f3n del exoma de 47 pacientes con esclerosis lateral amiotr\u00f3fica revel\u00f3 la existencia de mutaciones en el gen de la mol\u00e9cula SS18L1, tambi\u00e9n conocida como CREST. Las aplicaciones potenciales del hallazgo son comentadas en Chesi A, Staahl BT, Jovicic A, Couthouis J, Fasolino M, Rapahel AR, Yamazaki T. Exome sequencing to identify de novo [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[15,26],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1070"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=1070"}],"version-history":[{"count":0,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1070\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=1070"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=1070"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=1070"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}