{"id":1354,"date":"2013-09-15T19:51:43","date_gmt":"2013-09-15T23:51:43","guid":{"rendered":"http:\/\/blogviejo.sld.cu\/oserranob\/?p=1354"},"modified":"2013-09-15T19:51:43","modified_gmt":"2013-09-15T23:51:43","slug":"mutacion-asociada-a-leucemia-linfoblastica-aguda","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2013\/09\/15\/mutacion-asociada-a-leucemia-linfoblastica-aguda\/","title":{"rendered":"Mutaci\u00f3n asociada a leucemia linfobl\u00e1stica aguda"},"content":{"rendered":"<p><a href=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2013\/09\/2013-09-15-ALL.jpg\"><img loading=\"lazy\" class=\"alignright size-full wp-image-1412\" style=\"border: 1px solid black;margin: 5px\" src=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2013\/09\/2013-09-15-ALL.jpg\" alt=\"\" width=\"87\" height=\"71\" \/><\/a>Una mutaci\u00f3n recurrente en l\u00ednea germinal del gen <a title=\"Informaci\u00f3n sobre el gen\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/5079\" target=\"_blank\"><strong>PAX5<\/strong><\/a> parece conferir una mayor susceptibilidad a la <a title=\"Informaci\u00f3n sobre la enfermedad\" href=\"http:\/\/omim.org\/entry\/613065?search=ALL&amp;highlight=all\" target=\"_blank\"><strong>leucemia linfobl\u00e1stica aguda<\/strong><\/a> de c\u00e9lulas pre-B. Los mecanismos e implicaciones son comentados en <em>Shah S, Schrader KA, Waanders E, Timms AE, Vijai J, Miething C, et al. <a title=\"Texto completo en ingl\u00e9s\" href=\"http:\/\/www.nature.com\/ng\/journal\/vaop\/ncurrent\/full\/ng.2754.html\" target=\"_blank\"><strong>A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia<\/strong><\/a>. Nature Genetics 8 September 2013; doi:10.1038\/ng.2754<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Una mutaci\u00f3n recurrente en l\u00ednea germinal del gen PAX5 parece conferir una mayor susceptibilidad a la leucemia linfobl\u00e1stica aguda de c\u00e9lulas pre-B. Los mecanismos e implicaciones son comentados en Shah S, Schrader KA, Waanders E, Timms AE, Vijai J, Miething C, et al. A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[11,15,23,29],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1354"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=1354"}],"version-history":[{"count":0,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1354\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=1354"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=1354"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=1354"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}