{"id":1972,"date":"2014-09-23T04:10:40","date_gmt":"2014-09-23T04:10:40","guid":{"rendered":"http:\/\/blogs.sld.cu\/oserranob\/?p=1972"},"modified":"2014-09-23T11:14:20","modified_gmt":"2014-09-23T11:14:20","slug":"mutaciones-somaticas-afectan-al-cerebro-humano","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2014\/09\/23\/mutaciones-somaticas-afectan-al-cerebro-humano\/","title":{"rendered":"Mutaciones som\u00e1ticas afectan al cerebro humano"},"content":{"rendered":"<p><a href=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2014\/09\/2014-09-23-single-cell.jpg\"><img loading=\"lazy\" class=\"alignleft  wp-image-2022\" style=\"border: 1px solid black;margin: 5px\" src=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2014\/09\/2014-09-23-single-cell-150x144.jpg\" alt=\"\" width=\"90\" height=\"86\" \/><\/a>Diversos trastornos estructurales y del funcionamiento cerebral, que llegan hasta la hemimegaloencefalia con epilepsia y discapacidad intelectual, pueden ser la consecuencia de variaciones en la secuencia por mutaciones som\u00e1ticas durante el desarrollo prenatal del cerebro. Lea al respecto en Cai X, Evrony GD, Lehmann HS, Elhosary PC, Mehta BK, Poduri A,<em> et al<\/em>. <a title=\"Texto completo en ingl\u00e9s\" href=\"http:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247%2814%2900627-5\" target=\"_blank\">Single-Cell, Genome-wide Sequencing Identifies Clonal Somatic Copy-Number Variation in the Human Brain<\/a>. Cell Reports 2014;8(5):1280\u20131289.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Diversos trastornos estructurales y del funcionamiento cerebral, que llegan hasta la hemimegaloencefalia con epilepsia y discapacidad intelectual, pueden ser la consecuencia de variaciones en la secuencia por mutaciones som\u00e1ticas durante el desarrollo prenatal del cerebro. Lea al respecto en Cai X, Evrony GD, Lehmann HS, Elhosary PC, Mehta BK, Poduri A, et al. Single-Cell, Genome-wide [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[14,15,25,26,29],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1972"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=1972"}],"version-history":[{"count":4,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1972\/revisions"}],"predecessor-version":[{"id":1975,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/1972\/revisions\/1975"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=1972"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=1972"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=1972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}