{"id":2145,"date":"2015-01-13T06:04:48","date_gmt":"2015-01-13T06:04:48","guid":{"rendered":"http:\/\/blogs.sld.cu\/oserranob\/?p=2145"},"modified":"2015-01-14T21:42:50","modified_gmt":"2015-01-14T21:42:50","slug":"alelo-hla-relevante-en-enfermedad-intestinal-inflamatoria","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2015\/01\/13\/alelo-hla-relevante-en-enfermedad-intestinal-inflamatoria\/","title":{"rendered":"Alelo HLA relevante en enfermedad intestinal inflamatoria"},"content":{"rendered":"<p><a href=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2015\/01\/NG-IBD.jpg\"><img loading=\"lazy\" class=\"alignleft  wp-image-2189\" style=\"border: 1px solid black;margin: 5px\" src=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2015\/01\/NG-IBD-150x150.jpg\" alt=\"\" width=\"95\" height=\"95\" \/><\/a>El alelo <a title=\"Informaci\u00f3n sobre el gen\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/3123\" target=\"_blank\">HLA-DRB1<\/a>*01:03 parece tener un papel predominante tanto en la <a title=\"Informaci\u00f3n sobre la enfermedad\" href=\"http:\/\/omim.org\/entry\/266600?search=Crohn&amp;highlight=crohn\" target=\"_blank\">enfermedad de Crohn<\/a> como en la <a title=\"Informaci\u00f3n sobre la enfermedad\" href=\"http:\/\/omim.org\/entry\/266600?search=Crohn&amp;highlight=crohn\" target=\"_blank\">colitis ulcerativa<\/a>. Los resultados de un estudio de polimorfismos (SNP) han sido divulgados en Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, <em>et al<\/em>. <a title=\"Resumen en ingl\u00e9s\" href=\"http:\/\/www.nature.com\/ng\/journal\/vaop\/ncurrent\/full\/ng.3176.html\" target=\"_blank\">High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis<\/a>. Nature Genetics 2015; doi:10.1038\/ng.3176.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El alelo HLA-DRB1*01:03 parece tener un papel predominante tanto en la enfermedad de Crohn como en la colitis ulcerativa. Los resultados de un estudio de polimorfismos (SNP) han sido divulgados en Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, et al. High-density mapping of the MHC identifies a shared role for [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[15,29],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/2145"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=2145"}],"version-history":[{"count":5,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/2145\/revisions"}],"predecessor-version":[{"id":2168,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/2145\/revisions\/2168"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=2145"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=2145"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=2145"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}