{"id":2791,"date":"2016-02-20T22:41:50","date_gmt":"2016-02-20T22:41:50","guid":{"rendered":"http:\/\/blogs.sld.cu\/oserranob\/?p=2791"},"modified":"2016-02-21T06:26:02","modified_gmt":"2016-02-21T06:26:02","slug":"variantes-geneticas-en-defecto-del-septo-atrioventricular","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2016\/02\/20\/variantes-geneticas-en-defecto-del-septo-atrioventricular\/","title":{"rendered":"Variantes gen\u00e9ticas en defecto del septo atrioventricular"},"content":{"rendered":"<p style=\"text-align: justify\"><a href=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2016\/02\/septal-defect.jpeg\"><img loading=\"lazy\" class=\"alignleft size-thumbnail wp-image-2845\" style=\"border-width: 1px;margin: 5px\" src=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2016\/02\/septal-defect-150x144.jpeg\" alt=\"septal defect\" width=\"105\" height=\"101\" \/><\/a>Tras la secuenciaci\u00f3n del exoma, al menos seis genes (<a title=\"Informaci\u00f3n sobre el gen en Gene\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/25836\" target=\"_blank\">NIPBL<\/a>, <a title=\"Informaci\u00f3n sobre el gen en Gene\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/55636\" target=\"_blank\">CHD7<\/a>, <a title=\"Informaci\u00f3n sobre el gen en Gene\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/22995\" target=\"_blank\">CEP152<\/a>, <a title=\"Informaci\u00f3n sobre el gen en Gene\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/657\" target=\"_blank\">BMPR1a<\/a>, <a title=\"Informaci\u00f3n sobre el gen en Gene\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/23414\" target=\"_blank\">ZFPM2<\/a> y <a title=\"Informaci\u00f3n sobre el gen en Gene\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/gene\/4194\" target=\"_blank\">MDM4<\/a>) se asociaron con el <a title=\"Informaci\u00f3n sobre la enfermedad en OMIM\" href=\"http:\/\/omim.org\/entry\/606215\" target=\"_blank\">defecto del septo atrioventricular<\/a>, de acuerdo con D\u2019Alessandro LCA, Al Turki S, Manickaraj AK, Manase D, Mulder BJM, Bergin L, <em>et al<\/em>. <a title=\"Texto completo en ingl\u00e9s\" href=\"\/\/www.nature.com\/gim\/journal\/v18\/n2\/full\/gim201560a.html\" target=\"_blank\">Exome sequencing identifies rare variants in multiple genes in atrioventricular septal defect<\/a>. Genetics in Medicine 2016;18:189\u2013198.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tras la secuenciaci\u00f3n del exoma, al menos seis genes (NIPBL, CHD7, CEP152, BMPR1a, ZFPM2 y MDM4) se asociaron con el defecto del septo atrioventricular, de acuerdo con D\u2019Alessandro LCA, Al Turki S, Manickaraj AK, Manase D, Mulder BJM, Bergin L, et al. Exome sequencing identifies rare variants in multiple genes in atrioventricular septal defect. Genetics [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[13,14,15,29],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/2791"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=2791"}],"version-history":[{"count":5,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/2791\/revisions"}],"predecessor-version":[{"id":2861,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/2791\/revisions\/2861"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=2791"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=2791"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=2791"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}