{"id":3867,"date":"2017-07-23T04:27:51","date_gmt":"2017-07-23T04:27:51","guid":{"rendered":"http:\/\/blogs.sld.cu\/oserranob\/?p=3867"},"modified":"2017-07-23T04:51:35","modified_gmt":"2017-07-23T04:51:35","slug":"variantes-mutaciones-y-asociaciones-alzheimer-inteligencia-enfermedad-coronaria-cancer-de-pulmon-fuerza-muscular-infecciones-virales-lupus-autismo","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2017\/07\/23\/variantes-mutaciones-y-asociaciones-alzheimer-inteligencia-enfermedad-coronaria-cancer-de-pulmon-fuerza-muscular-infecciones-virales-lupus-autismo\/","title":{"rendered":"Nuevas variantes, mutaciones y asociaciones"},"content":{"rendered":"<p style=\"text-align: justify\">&#8211; <a title=\"Nature Genetics 2017; doi:10.1038\/ng.3916 \" href=\"http:\/\/www.nature.com\/ng\/journal\/vaop\/ncurrent\/full\/ng.3916.html\" target=\"_blank\">Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer&#8217;s disease<\/a><br \/>\n&#8211; <a title=\"Nature Genetics 2017;49:1107\u20131112. \" href=\"http:\/\/www.nature.com\/ng\/journal\/v49\/n7\/full\/ng.3869.html\" target=\"_blank\">Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence<\/a><br \/>\n&#8211; <a title=\"Nature Genetics 2017;49:1113\u20131119. \" href=\"http:\/\/www.nature.com\/ng\/journal\/v49\/n7\/full\/ng.3874.html\" target=\"_blank\">Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms<\/a><br \/>\n&#8211; <a title=\"Nature Genetics 2017;49:1126\u20131132. \" href=\"http:\/\/www.nature.com\/ng\/journal\/v49\/n7\/full\/ng.3892.html\" target=\"_blank\">Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes<\/a><br \/>\n&#8211; <a title=\"Nature Communications 2017;8:16015. \" href=\"http:\/\/www.nature.com\/articles\/ncomms16015\" target=\"_blank\">Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness<\/a><br \/>\n&#8211; <a title=\"PNAS 2017; doi: 10.1073\/pnas.1704259114\" href=\"http:\/\/www.pnas.org\/content\/early\/2017\/07\/13\/1704259114.full\" target=\"_blank\">Severe viral respiratory infections in children with IFIH1 loss-of-function mutations<\/a><br \/>\n&#8211; <a title=\"Nature Communications 2017;8:16021 \" href=\"http:\/\/www.nature.com\/articles\/ncomms16021\" target=\"_blank\">Transancestral mapping and genetic load in systemic lupus erythematosus<\/a><br \/>\n&#8211; <a title=\"Nature Neuroscience 2017; doi:10.1038\/nn.4598 \" href=\"http:\/\/www.nature.com\/neuro\/journal\/vaop\/ncurrent\/full\/nn.4598.html\" target=\"_blank\">Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8211; Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer&#8217;s disease &#8211; Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence &#8211; Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms &#8211; Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[11,15,23,25,26,28,29],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/3867"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=3867"}],"version-history":[{"count":6,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/3867\/revisions"}],"predecessor-version":[{"id":3911,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/3867\/revisions\/3911"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=3867"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=3867"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=3867"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}