{"id":3979,"date":"2017-09-23T17:30:26","date_gmt":"2017-09-23T17:30:26","guid":{"rendered":"http:\/\/blogs.sld.cu\/oserranob\/?p=3979"},"modified":"2017-09-26T04:37:53","modified_gmt":"2017-09-26T04:37:53","slug":"corrigen-mutacion-en-embriones-humanos-no-implantados","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2017\/09\/23\/corrigen-mutacion-en-embriones-humanos-no-implantados\/","title":{"rendered":"Corrigen mutaci\u00f3n en embriones humanos no implantados"},"content":{"rendered":"<p style=\"text-align: justify\"><a href=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2017\/09\/Embryo.jpg\"><img loading=\"lazy\" class=\"alignleft wp-image-4000 size-full\" style=\"border-width: 1px;margin: 5px\" title=\"(c) Ma H et al. Nature 217\" src=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2017\/09\/Embryo.jpg\" alt=\"Embryo\" width=\"85\" height=\"68\" \/><\/a>La correcci\u00f3n preimplantatoria de una mutaci\u00f3n en el gen <a title=\"Informaci\u00f3n sobre el gen en Gene\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/gene\/4607\" target=\"_blank\">MYBPC3<\/a> en embriones humanos, por medio de la tecnolog\u00eda CRISPR\u2013Cas9, ha sido conseguida con buenas eficiencia, precisi\u00f3n y seguridad. La modulaci\u00f3n del estadio del ciclo celular donde se indujeron las roturas de la doble h\u00e9lice evit\u00f3 el mosaicismo, seg\u00fan Ma H, Marti-Gutierrez N, Park SW, Wu J, Lee Y, Suzuki K, <em>et al<\/em>. <a title=\"Texto completo en ingl\u00e9s\" href=\"http:\/\/www.nature.com\/nature\/journal\/v548\/n7668\/full\/nature23305.html\" target=\"_blank\">Correction of a pathogenic gene mutation in human embryos<\/a>. Nature 2017;548:413\u2013419.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>La correcci\u00f3n preimplantatoria de una mutaci\u00f3n en el gen MYBPC3 en embriones humanos, por medio de la tecnolog\u00eda CRISPR\u2013Cas9, ha sido conseguida con buenas eficiencia, precisi\u00f3n y seguridad. La modulaci\u00f3n del estadio del ciclo celular donde se indujeron las roturas de la doble h\u00e9lice evit\u00f3 el mosaicismo, seg\u00fan Ma H, Marti-Gutierrez N, Park SW, Wu [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[44,23,32],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/3979"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=3979"}],"version-history":[{"count":3,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/3979\/revisions"}],"predecessor-version":[{"id":4001,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/3979\/revisions\/4001"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=3979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=3979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=3979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}