{"id":4758,"date":"2020-07-31T18:11:19","date_gmt":"2020-07-31T18:11:19","guid":{"rendered":"http:\/\/blogs.sld.cu\/oserranob\/?p=4758"},"modified":"2020-07-31T18:11:19","modified_gmt":"2020-07-31T18:11:19","slug":"pwas-nuevos-estudios-de-asociacion-con-funcion-proteica","status":"publish","type":"post","link":"https:\/\/blogs.sld.cu\/oserranob\/2020\/07\/31\/pwas-nuevos-estudios-de-asociacion-con-funcion-proteica\/","title":{"rendered":"PWAS, nuevos estudios de asociaci\u00f3n con funci\u00f3n proteica"},"content":{"rendered":"<p style=\"text-align: justify\"><a href=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2020\/07\/PWAS.jpg\"><img loading=\"lazy\" class=\"alignleft wp-image-4759 size-full\" style=\"border-width: 1px;margin: 5px\" title=\"(c) Brandes N, et al. Genome Biology, 2020.\" src=\"https:\/\/blogs.sld.cu\/oserranob\/files\/2020\/07\/PWAS.jpg\" alt=\"PWAS\" width=\"85\" height=\"110\" \/><\/a>Los estudios de asociaci\u00f3n de proteoma completo (en ingl\u00e9s <em>Proteome-Wide Association Study<\/em>, PWAS) buscan relaciones genotipo-fenotipo mediadas por alteraciones en la funci\u00f3n de las prote\u00ednas. Emplean t\u00e9cnicas de aprendizaje autom\u00e1tico y modelos probabil\u00edsticos, de acuerdo con la descripci\u00f3n en Brandes N, Linial B, Linial M. <a title=\"Texto completo en ingl\u00e9s\" href=\"https:\/\/genomebiology.biomedcentral.com\/articles\/10.1186\/s13059-020-02089-x\" target=\"_blank\">PWAS: proteome-wide association study\u2014linking genes and phenotypes by functional variation in proteins<\/a>. Genome Biology, 2020;21:173.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Los estudios de asociaci\u00f3n de proteoma completo (en ingl\u00e9s Proteome-Wide Association Study, PWAS) buscan relaciones genotipo-fenotipo mediadas por alteraciones en la funci\u00f3n de las prote\u00ednas. Emplean t\u00e9cnicas de aprendizaje autom\u00e1tico y modelos probabil\u00edsticos, de acuerdo con la descripci\u00f3n en Brandes N, Linial B, Linial M. PWAS: proteome-wide association study\u2014linking genes and phenotypes by functional variation [&hellip;]<\/p>\n","protected":false},"author":125,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[29,41],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/4758"}],"collection":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/users\/125"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/comments?post=4758"}],"version-history":[{"count":1,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/4758\/revisions"}],"predecessor-version":[{"id":4760,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/posts\/4758\/revisions\/4760"}],"wp:attachment":[{"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/media?parent=4758"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/categories?post=4758"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sld.cu\/oserranob\/wp-json\/wp\/v2\/tags?post=4758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}